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. 2009 Jul;1(1):a000026.
doi: 10.1101/cshperspect.a000026.

Discovering NF-kappaB

David Baltimore  1
Affiliations

Discovering NF-kappaB

David Baltimore. Cold Spring Harb Perspect Biol. 2009 Jul.

Abstract

David Baltimore recalls the experiments that led to the discovery of the NF-kappaB transcription factor more than 20 years ago.

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References

    1. Baeuerle PA, Baltimore D 1988a. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor. Cell 53:211–217 - PubMed
    1. Baeuerle PA, Baltimore D 1988b. IκB: a specific inhibitor of the NF-κB transcription factor. Science 242:540–546 - PubMed
    1. Inlay M, Alt FW, Baltimore D, Xu Y 2002. Essential roles of the κ light chain intronic enhancer and 3’ enhancer in κ rearrangement and demethylation. Nature Immunology 3:463–468 - PubMed
    1. Queen C, Baltimore D 1983. Immunoglobulin gene transcription is activated by downstream sequence elements. Cell 33:741–748 - PubMed
    1. Sen R, Baltimore D 1986a. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46:705–716 - PubMed

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