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. 2009 Jan;5(1):36-9.
doi: 10.2174/157340309787048095.

Anaerobic bacteria as a cause of mycotic aneurysm of the aorta: microbiology and antimicrobial therapy

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Anaerobic bacteria as a cause of mycotic aneurysm of the aorta: microbiology and antimicrobial therapy

Itzhak Brook. Curr Cardiol Rev. 2009 Jan.

Abstract

This review summarizes the microbiology, and antimicrobial management of mycotic aneurysm of the aorta (MAA) due to anaerobic bacteria. Anaerobic bacteria are an uncommon but important cause of MAA. Most cases of anaerobic MAA are caused anaerobic gram-negative bacilli (mostly B. fragilis group), Clostridium spp. (mostly Clostridium septicum, and Propionobacterium spp. (mostly P. acnes). Clostridial infection is frequently associated with gastrointestinal or hematologic malignancy. A review of all the reported cases is presented. Treatment of MAA involving anaerobic bacteria includes the use of antimicrobial effective against these organisms.

Keywords: Anaerobic bacteria; Bacteroides fragilis; Clostridium spp.; Propionibacterium acnes.; aorta; mycotic aneurysm.

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