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. 2010 Jan 21;46(3):454-6.
doi: 10.1039/b917758b. Epub 2009 Nov 11.

Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media

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Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media

José Alemán et al. Chem Commun (Camb). .

Abstract

An efficient cyclization of alkyne-acids to enol-lactones catalyzed by anticancer platinum(II) and platinum(IV) compounds is described. These compounds are not only DNA-binding complexes; they can also catalyze reactions in solvents such as acetone, methanol, water or blood plasma.

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