Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Jan 14;16(2):251-5.
doi: 10.3748/wjg.v16.i2.251.

Reinfection rate and endoscopic changes after successful eradication of Helicobacter pylori

Kum Hei Ryu  1 , Sun Young Yi, Youn Ju Na, Su Jung Baik, Su Jin Yoon, Hae-Sun Jung, Hyun Joo Song
Affiliations

Reinfection rate and endoscopic changes after successful eradication of Helicobacter pylori

Kum Hei Ryu et al. World J Gastroenterol. .

Abstract

Aim: To determine the long-term outcomes regarding reinfection with Helicobacter pylori (H. pylori) and endoscopic changes after successful H. pylori eradication.

Methods: From June 1994 to January 2007, 186 patients (M:F = 98:88; mean age 50.0 +/- 11.4 years), in whom H. pylori had been successfully eradicated, were enrolled. The mean duration of follow up was 41.2 +/- 24.0 mo.

Results: H. pylori reinfection occurred in 58 patients (31.2%). The average annual reinfection rate was 9.1% per patient year. No recurrence of peptic ulcer was detected at the follow up endoscopy. There were no significant differences between the H. pylori eradication regimens for the reinfection rate and no significant differences in endoscopic findings between the H. pylori-recurred group and the H. pylori-cured group.

Conclusion: The reinfection rate in Korea is 9.1% which represents a decreasing trend. There was no relationship between H. pylori infection status and changes in endoscopic findings. There was also no recurrence or aggravation of ulcers.

PubMed Disclaimer

References

    1. Okimoto T, Murakami K, Sato R, Miyajima H, Nasu M, Kagawa J, Kodama M, Fujioka T. Is the recurrence of Helicobacter pylori infection after eradication therapy resultant from recrudescence or reinfection, in Japan. Helicobacter. 2003;8:186–191. - PubMed
    1. Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med. 2002;347:1175–1186. - PubMed
    1. Cheon JH, Kim N, Lee DH, Kim JM, Kim JS, Jung HC, Song IS. Long-term outcomes after Helicobacter pylori eradication with second-line, bismuth-containing quadruple therapy in Korea. Eur J Gastroenterol Hepatol. 2006;18:515–519. - PubMed
    1. Gisbert JP. The recurrence of Helicobacter pylori infection: incidence and variables influencing it. A critical review. Am J Gastroenterol. 2005;100:2083–2099. - PubMed
    1. Hildebrand P, Bardhan P, Rossi L, Parvin S, Rahman A, Arefin MS, Hasan M, Ahmad MM, Glatz-Krieger K, Terracciano L, et al. Recrudescence and reinfection with Helicobacter pylori after eradication therapy in Bangladeshi adults. Gastroenterology. 2001;121:792–798. - PubMed

Substances