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Review
. 2009 May-Jun;1(3):216-21.
doi: 10.4161/mabs.1.3.8593.

Ustekinumab

Oya Cingoz  1
Affiliations
Review

Ustekinumab

Oya Cingoz. MAbs. 2009 May-Jun.

Abstract

Ustekinumab is an anti-IL12/23 IgG1 kappa human monoclonal antibody currently undergoing US Food and Drug Administration review for use as a psoriasis treatment. The candidate has also been evaluated in Phase 2 studies as a treatment for psoriatic arthritis, Crohn disease and multiple sclerosis.In large clinical trials, ustekinumab has proven effective for treating moderate to severe plaque psoriasis. Although long-term follow-up studies are needed to address safety concerns, the hopes are high for psoriasis treatment. Ustekinumab has recently been approved for marketing in Canada and Europe.

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