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Comparative Study
. 1977 Nov;37(2):271-6.
doi: 10.1099/0022-1317-37-2-271.

An assessment by competition hybridization of the sequence homology between the RNAs of the seven serotypes of FMDV

K J Robson, T J Harris, F Brown
Comparative Study

An assessment by competition hybridization of the sequence homology between the RNAs of the seven serotypes of FMDV

K J Robson et al. J Gen Virol. 1977 Nov.

Abstract

A comparison has been made of the RNAs of the seven serotypes of foot-and-mouth disease virus (FMDV) by competition hybridization. Homology among the three European serotypes A, O, C and the Asia I serotype was 60 to 70%. Similar homologies were found among the three Southern African Territories serotypes (SAT I, SAT 2, SAT 3), but homology between the two groups was much lower (25 to 40%). Homology between the RNAs of subtypes within serotypes A and O was greater than 70%. Double competition experiments with the Eropean serotypes indicate sharing of nucleotide sequences.

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