Review
doi: 10.1016/j.cbpa.2009.11.026.
Epub 2010 Jan 12.
Design strategies for the creation of artificial metalloenzymes
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- PMID: 20071213
- DOI: 10.1016/j.cbpa.2009.11.026
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Review
Design strategies for the creation of artificial metalloenzymes
Curr Opin Chem Biol.
2010 Apr.
Abstract
In recent years, several complementary strategies have been implemented for the creation and optimization of artificial metalloenzymes. Selected examples outline the pros and cons of five different approaches: catalytic antibodies, computational design, directed evolution, artificial metal-cofactors and DNAzymes.
Copyright 2010 Elsevier Ltd. All rights reserved.
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