Successful use of the "unacceptable" heart donor
- PMID: 2007168
Successful use of the "unacceptable" heart donor
Abstract
Chronic shortage of donor organs has heightened interest in new strategies for increasing donor availability. Unacceptable hearts for transplant have previously been characterized by donor age greater than 40 years, more than 20% donor/recipient weight mismatch, ischemic time more than 4 hours, and the presence of coronary artery disease. A series of 185 consecutive orthotopic heart transplants were retrospectively examined. A significant number of donor hearts used were unacceptable by one or more of the above criteria. Our current approach is to match donors to recipients using a wide range of criteria. Donors are now accepted from any location in North America. We have accepted donors more than 55 years of age and donors weighing less than 50% of the recipient's body weight. Because of the chronic shortage of donor organs, donor criteria have been effectively liberalized, thereby increasing the donor pool without compromising the overall results of heart transplantation.
Similar articles
-
Three-year survival rates for all consecutive heart-only and lung-only transplants performed in Eurotransplant, 1997-1999.Clin Transpl. 2003:89-100. Clin Transpl. 2003. PMID: 15387100
-
Impact of donor-to-recipient weight ratio on survival after heart transplantation: analysis of the United Network for Organ Sharing Database.Circulation. 2008 Sep 30;118(14 Suppl):S83-8. doi: 10.1161/CIRCULATIONAHA.107.756866. Circulation. 2008. PMID: 18824775
-
Posttransplantation hemodynamics and exercise function are not affected by body-size matching of donor and recipient.J Heart Lung Transplant. 1993 Sep-Oct;12(5):770-8. J Heart Lung Transplant. 1993. PMID: 8241214
-
[Controversies in the selection of donors in heart transplants].G Ital Cardiol. 1992 Dec;22(12):1405-14. G Ital Cardiol. 1992. PMID: 1294424 Review. Italian.
-
Marginal donor grafts in heart transplantation: lessons learned from 25 years of experience.Transpl Int. 2008 Feb;21(2):113-25. doi: 10.1111/j.1432-2277.2007.00603.x. Epub 2007 Dec 5. Transpl Int. 2008. PMID: 18062790 Review.
Cited by
-
Long term follow up of severely ill patients who underwent urgent cardiac transplantation.BMJ. 1993 Jan 9;306(6870):98-101. doi: 10.1136/bmj.306.6870.98. BMJ. 1993. PMID: 8435650 Free PMC article.
-
Bioprosthetic Aortic Valve Replacement in a Donor Heart before Orthotopic Heart Transplantation.Tex Heart Inst J. 2017 Apr 1;44(2):135-137. doi: 10.14503/THIJ-16-5789. eCollection 2017 Apr. Tex Heart Inst J. 2017. PMID: 28461800 Free PMC article.
-
Prognostic Value of Ambulatory Status at Transplant in Older Heart Transplant Recipients: Implications for Organ Allocation Policy.J Korean Med Sci. 2025 Jan 20;40(3):e14. doi: 10.3346/jkms.2025.40.e14. J Korean Med Sci. 2025. PMID: 39834223 Free PMC article.
MeSH terms
LinkOut - more resources
Medical