Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Dec;2(4):207-10.
doi: 10.3342/ceo.2009.2.4.207. Epub 2009 Dec 31.

Basaloid squamous cell carcinoma in nasal cavity

Joong Seob Lee  1 , Il Ju Ko, Sun-Young Jun, Jin Young Kim
Affiliations

Basaloid squamous cell carcinoma in nasal cavity

Joong Seob Lee et al. Clin Exp Otorhinolaryngol. 2009 Dec.

Abstract

Basaloid squamous cell carcinoma (BSCC) is often founded in the head and neck region. However, BSCC in the sinonasal tract is rare. We report here on the case of a 58-yr-old woman who presented with nasal obstruction and epistaxis. Computed tomography and examination of the nasal cavity revealed a tumor mass that originated from the right inferior turbinate with erosion of the nasal floor. The tumor that was attached to the inferior turbinate, the lateral nasal wall and the eroded right side hard palate, and so all this was resected. Histopathologic examination of the excised tumor confirmed BSCC in the nasal cavity. We report here on a nasal cavity BSCC that was treated with partial maxillectomy only.

Keywords: Basaloid squamous cell carcinoma; Maxillectomy; Sinonasal tract.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Coronal & sagittal CT of the paranasal sinus shows the right nasal cavity mass (arrows). The tumor mass showing focal enhancement with bone erosion at the inferior turbinate and hard palate. (A) Sagittal view. (B) Coronal view.
Fig. 2
Fig. 2
Pathologic findings. (A) Irregular lobules of basaloid cells with comedo-type necrosis (arrow; H&E, ×40). (B) Abundant intercellular hyaline globules (white arrow) and multifocal keratinization (black arrow; H&E, ×200). (C) Nest of basaloid cells with peripheral palisading of the nuclei (arrows; H&E, ×400).
Fig. 3
Fig. 3
Immunohistochemical findings showing the basaloid squamous cell features of the tumor cells (×400). (A) Nuclear immunoreactivity on the p63 staining with a brownish color (arrow). (B) Cytoplasmic and cytoplasmic membranous immunoreactivities on the high molecular weight cytokeratin staining with a brownish color (arrow). (C) No immunoreactivity on the chromogranin & CD56 staining.
See this image and copyright information in PMC

References

    1. Lu SY, Eng HL, Huang CC, Chien CY, Lui CC, Lin JW. Basaloid squamous cell carcinoma of the sinonasal tract: report of two cases. Otolaryngol Head Neck Surg. 2006 May;134(5):883–885. - PubMed
    1. Wain SL, Kier R, Vollmer RT, Bossen EH. Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases. Hum Pathol. 1986 Nov;17(11):1158–1166. - PubMed
    1. Coppola D, Catalano E, Tang CK, Elfenbein IB, Harwick R, Mohr R. Basaloid squamous cell carcinoma of floor of mouth. Cancer. 1993 Oct;72(8):2299–2305. - PubMed
    1. Raslan WF, Barnes L, Krause JR, Contis L, Killeen R, Kapadia SB. Basaloid squamous cell carcinoma of the head and neck: a clinicopathologic and flow cytometric study of 10 new cases with review of the English literature. Am J Otolaryngol. 1994 May–Jun;15(3):204–211. - PubMed
    1. Paulino AF, Singh B, Shah JP, Huvos AG. Basaloid squamous cell carcinoma of the head and neck. Laryngoscope. 2000 Sep;110(9):1479–1482. - PubMed