Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Nov;76(11):1151-3.
doi: 10.1007/s12098-009-0287-7. Epub 2010 Jan 14.

Pheochromocytoma in children and adolescents

H K Ganesh  1 , Shrikrishna V Acharya, Joe Goerge, Tushar R Bandgar, Padma S Menon, Nalini S Shah
Affiliations

Pheochromocytoma in children and adolescents

H K Ganesh et al. Indian J Pediatr. 2009 Nov.

Abstract

Eleven subjects aged <20 yr with histologically proven pheochromocytoma between 1987 and 2006 were analyzed. Family history was present in 18%. In 2 patients, pheochromocytoma was part of VHL and in one it was associated with MEN 2. Twenty four hour urine VMA level was elevated in 100% and metanephrine level in 73%. CT/ MRI were showing the tumor in all. Prazosin extended release tablets (maximum 30 mg/day) were used in 73% and doxazosin (maximum 12 mg/ day) in 27%. Intraoperative BP fluctuations were seen in 27%. All were biochemically cured after surgery. Preoperative á blockade with extended release prazosin and doxazosin were effective in controlling perioperative BP fluctuations. Hence these drugs can be used in children and adolescents without fear of postoperative hypotension.

PubMed Disclaimer

References

    1. JAMA. 2002 Mar 20;287(11):1427-34 - PubMed
    1. Endocr Rev. 2003 Aug;24(4):539-53 - PubMed
    1. Int Surg. 2002 Jul-Sep;87(3):191-4 - PubMed
    1. Indian Pediatr. 2002 Jan;39(1):51-7 - PubMed
    1. J Urol. 1997 Apr;157(4):1208-12 - PubMed

MeSH terms

LinkOut - more resources