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. 2010:605:205-12.
doi: 10.1007/978-1-60327-360-2_14.

Vesicular phospholipid gels

Martin Brandl  1
Affiliations

Vesicular phospholipid gels

Martin Brandl. Methods Mol Biol. 2010.

Abstract

Highly concentrated phospholipid dispersions of vesicular morphology, Vesicular phospholipid Gels (VPGs) are of importance for sustained release of drugs upon implantation, or, upon transfer into SUV-dispersions, for drug delivery upon i.v. injection. Here the formation of homogeneous lipid and lipid/drug-blends is described as well as the preparation of VPGs by high-pressure homogenization, along with remote loading via "passive loading".

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