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Comment
. 2006 Nov;4(11):e397.
doi: 10.1371/journal.pbio.0040397. Epub 2006 Oct 24.

Too long, too short, or just right: glycosphingolipid-protein binding varies with acyl chain length

Comment

Too long, too short, or just right: glycosphingolipid-protein binding varies with acyl chain length

Richard Robinson. PLoS Biol. 2006 Nov.
No abstract available

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The sphingosine chain of GSL is blocked from entering the tight confines of the GLTP hydrophobic tunnel because the long acyl chain, which enters first, is forced into a serpentine-like conformation within the tunnel.

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