doi: 10.1016/j.fitote.2010.01.001.
Epub 2010 Jan 15.
New neo-clerodane diterpenoids from Scutellaria barbata with cytotoxic activities
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- PMID: 20079810
- DOI: 10.1016/j.fitote.2010.01.001
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New neo-clerodane diterpenoids from Scutellaria barbata with cytotoxic activities
Fitoterapia.
2010 Oct.
Abstract
Two new neo-clerodane diterpenoids have been isolated from the whole plant of Scutellaria barbata D. Don, and their structures were established by detailed spectral analyses as scutehenanine H (1) and 6-(2,3-epoxy-2-isopropyl-n-propoxyl)barbatin C (2). In vitro, the isolated two new compounds showed significant cytotoxic activities against three human cancer lines, and gave IC(50) values in the range OF 2.0-4.2 μΜ.
Copyright © 2010 Elsevier B.V. All rights reserved.
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