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Comment
. 2010 Jan 19;107(3):955-6.
doi: 10.1073/pnas.0913433107. Epub 2010 Jan 11.

Gene amplification delivers glyphosate-resistant weed evolution

Stephen B Powles  1
Affiliations
Comment

Gene amplification delivers glyphosate-resistant weed evolution

Stephen B Powles. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1
Fig. 1
Glyphosate resistance resulting from gene amplification. In a susceptible individual (A), the normal number of EPSPS gene copies (yellow dots on chromosomes) produce EPSPS (yellow) in leaf chloroplasts that is targeted and overwhelmed by the normal usage rate of glyphosate (red), and the plant dies. In a resistant individual (B) with amplified EPSPS gene copies present on multiple chromosomes, there is increased EPSPS, and the normal glyphosate rate cannot inhibit all of the available EPSPS.
See this image and copyright information in PMC

Comment on

  • Gene amplification confers glyphosate resistance in Amaranthus palmeri.
    Gaines TA, Zhang W, Wang D, Bukun B, Chisholm ST, Shaner DL, Nissen SJ, Patzoldt WL, Tranel PJ, Culpepper AS, Grey TL, Webster TM, Vencill WK, Sammons RD, Jiang J, Preston C, Leach JE, Westra P. Gaines TA, et al. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1029-34. doi: 10.1073/pnas.0906649107. Epub 2009 Dec 14. Proc Natl Acad Sci U S A. 2010. PMID: 20018685 Free PMC article.

References

    1. Powles SB. Evolved glyphosate-resistant weeds around the world: Lessons to be learnt. Pest Manag Sci. 2008;64:360–365. - PubMed
    1. Gaines TA, et al. Gene amplification confers glyphosate resistance in Amaranthus palmeri. Proc Natl Acad Sci USA. 2010;107:1029–1034. - PMC - PubMed
    1. Dill GM, Cajacob CA, Padgette SR. Glyphosate-resistant crops: Adoption, use and future considerations. Pest Manag Sci. 2008;64:326–331. - PubMed
    1. Powles SB, Preston C. Evolved glyphosate resistance in plants: Biochemical and genetic basis of resistance. Weed Technol. 2006;20:282–289.
    1. Culpepper AS, et al. Glyphosate-resistant Palmer amaranth (Amaranthus palmeri) confirmed in Georgia. Weed Sci. 2006;54:620–626.

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