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. 2011 Jan;125(1):143-7.
doi: 10.1007/s00414-009-0404-1. Epub 2010 Jan 15.

Software for Y-haplogroup predictions: a word of caution

Marina Muzzio  1 , Virginia Ramallo, Josefina M B Motti, Maria R Santos, Jorge S López Camelo, Graciela Bailliet
Affiliations

Software for Y-haplogroup predictions: a word of caution

Marina Muzzio et al. Int J Legal Med. 2011 Jan.

Abstract

The development of online software designed for genetic studies has been exponentially growing, providing numerous benefits to the scientific community. However, they should be used with care, since some require adjustments. The efficiency of two programs for haplogroup prediction was tested with 119 samples of known haplotypes and haplogroups from Argentine populations. Quantitative estimates of the predictive quality of both software systems were computed with the uncertainty coefficient; and sensitivity, specificity, positive, and negative likelihood ratios were also calculated to assert the reliability of both programs, showing high probabilities of assigning an incorrect haplogroup.

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References

    1. Am J Hum Genet. 2008 Apr;82(4):873-82 - PubMed
    1. Am J Hum Genet. 1998 Dec;63(6):1862-71 - PubMed
    1. Lancet. 1999 Nov 13;354(9191):1721-4 - PubMed
    1. PLoS Comput Biol. 2008 Jun 13;4(6):e1000093 - PubMed
    1. Am J Hum Genet. 1999 Dec;65(6):1623-38 - PubMed

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