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. 2010 Jan;9(1):4-5.
doi: 10.1016/S1474-4422(09)70330-8.

Alzheimer's disease: progress in prediction

Ronald C Petersen  1
Affiliations

Alzheimer's disease: progress in prediction

Ronald C Petersen. Lancet Neurol. 2010 Jan.
No abstract available

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Figures

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Hypothetical progression of pathological and clinical events with associated detection techniques, imaging or biomarkers, that lead to Alzheimer’s disease. All measures are portrayed with increasing degrees of abnormality on the ordinate. EMCI: early MCI; LMCI: late MCI; CSF: cerebrospinal fluid; FDG PET: fluorodeoxyglucose positron emission tomography; MRI: magnetic resonance imaging; ADL: activities of daily living.
See this image and copyright information in PMC

References

    1. Petersen R, Knopman D, Boeve B, Geda Y, Ivnik R, Smith G, et al. Mild Cognitive Impairment: Ten Years Later. Archives of Neurology. 2009 in press. - PMC - PubMed
    1. Petersen RC, Aisen PS, Beckett LA, Donahue MJ, Gamst AC, Harvey DJ, et al. Alzheimer’s Disease Neuroimaging Initiative (ADNI): Clinical Characterization. Neurology. 2009 (in press) - PMC - PubMed
    1. Mormino EC, Kluth JT, Madison CM, Rabinovici GD, Baker SL, Miller BL, et al. Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects. Brain. 2009 May;132(Pt 5):1310–23. - PMC - PubMed
    1. Jack C, Jr, Low V, Weigand S, Wiste H, Senjem M, Knopman D, et al. Serial PiB and MRI in normal, mild cognitive impairment and Alzheimer’s disease: implications for sequence of pathological events in Alzheimer’s disease. Brain. 2009;132:1355–65. - PMC - PubMed
    1. Shaw LM, Vanderstichele H, Knapik-Czajka M, Clark CM, Aisen PS, Petersen RC, et al. Cerebrospinal fluid biomarker signature in Alzheimer’s disease neuroimaging initiative subjects. Ann Neurol. 2009 Apr;65(4):403–13. - PMC - PubMed

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