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. 1977 Sep 9;154(3):269-77.
doi: 10.1007/BF00571282.

Ertosterol biosynthesis in Saccharomyces cerevisiae: mutants deficient in the early steps of the pathway

F Karst, F Lacroute

Ertosterol biosynthesis in Saccharomyces cerevisiae: mutants deficient in the early steps of the pathway

F Karst et al. Mol Gen Genet. .

Abstract

Thermosensitive mutants, auxotrophic for ergosterol synthesis, have been isolated, analyzed genetically and their enzymatic deficiencies investigated. These mutants were classified into seven unlinked complementation groups. These groupes lack the following enzymatic activities: squalene epoxidase (erg 1), 2,3-oxidosqualene-lanosterol cyclase (erg 7), phosphomevalonic kinase (erg 8), mevalonic kinase (erg12) and squalene synthetase (erg 9, erg 10, erg 11).

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References

    1. J Cell Comp Physiol. 1953 Feb;41(1):23-36 - PubMed
    1. J Bacteriol. 1972 Jan;109(1):34-43 - PubMed
    1. J Biol Chem. 1960 Feb;235:326-32 - PubMed
    1. Biochim Biophys Acta. 1970 Dec 16;220(3):463-8 - PubMed
    1. J Biol Chem. 1970 Apr 10;245(7):1670-4 - PubMed

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