Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010 Feb;7(2):94-100.
doi: 10.1038/nrurol.2009.263. Epub 2010 Jan 19.

Testicular germline stem cells

Affiliations
Review

Testicular germline stem cells

Kehkooi Kee et al. Nat Rev Urol. 2010 Feb.

Abstract

Stem cells have the ability to both differentiate into other mature cell types and maintain an undifferentiated state by self-renewal. These unique properties form the basis for stem cell use in organ replacement and tissue regeneration in clinical medicine. Currently, embryonic stem cells are the best-studied stem cell type. However alternative stem cells such as induced pluripotent stem cells and other adult stem cells are also being actively investigated for their potential for cell-based therapy. Among adult stem cells, emerging research has focused on evaluating the pluripotency potential of testis stem cells. To date, stem cells with embryonic-like potential have been created from adult testis germ cells. These cells could provide patient-specific, non-embryo-derived stem cells for men in the future.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Nature. 2004 Mar 11;428(6979):145-50 - PubMed
    1. Int Rev Physiol. 1980;22:41-115 - PubMed
    1. PLoS Med. 2006 Feb;3(5):e143 - PubMed
    1. Cell. 2004 Dec 29;119(7):1001-12 - PubMed
    1. Stem Cells Dev. 2009 Oct;18(8):1115-26 - PubMed