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Comparative Study
. 1991 Jan-Feb;31(1):92-6.

[The action of the tumor necrosis factor (TNF) on the recovery processes of hemopoietic colony-forming cells in irradiated mice]

[Article in Russian]
O V Semina, T N Semenets, S A Chuvpilo, V G Korobko, A M Povererennyĭ
  • PMID: 2008530
Comparative Study

[The action of the tumor necrosis factor (TNF) on the recovery processes of hemopoietic colony-forming cells in irradiated mice]

[Article in Russian]
O V Semina et al. Radiobiologiia. 1991 Jan-Feb.

Abstract

The influence of a tumor-necrotic factor (TNF) on the CFUs population has been studied normally and after irradiation. An inhibitory effect on the pool of the seven-day and doubling of the yield of the eleven-day colonies have been observed in mice received TNF 20 h before bone marrow removal as compared with the controls. The kinetics of restoration of bone marrow cellularity and CFUs number in mouse donors treated with TNF 20 h before irradiation (5.0 Gy) has demonstrated the stimulatory effect of the agent on both indices.

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