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. 2010 Jan 8;140(1):19-23.
doi: 10.1016/j.cell.2009.12.029.

Engineering static and dynamic control of synthetic pathways

William J Holtz  1 , Jay D Keasling
Affiliations
Free article

Engineering static and dynamic control of synthetic pathways

William J Holtz et al. Cell. .
Free article

Abstract

Maximizing the production of a desired small molecule is one of the primary goals in metabolic engineering. Recent advances in the nascent field of synthetic biology have increased the predictability of small-molecule production in engineered cells growing under constant conditions. The next frontier is to create synthetic pathways that adapt to changing environments.

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