Engineering static and dynamic control of synthetic pathways
- PMID: 20085699
- DOI: 10.1016/j.cell.2009.12.029
Engineering static and dynamic control of synthetic pathways
Abstract
Maximizing the production of a desired small molecule is one of the primary goals in metabolic engineering. Recent advances in the nascent field of synthetic biology have increased the predictability of small-molecule production in engineered cells growing under constant conditions. The next frontier is to create synthetic pathways that adapt to changing environments.
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