Review
doi: 10.1016/j.vaccine.2010.01.007.
Epub 2010 Jan 17.
Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediated mechanism
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- PMID: 20085834
- DOI: 10.1016/j.vaccine.2010.01.007
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Review
Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediated mechanism
Vaccine.
.
Abstract
We report 3 cases of orchitis following vaccination with mumps-measles-rubella (MMR) vaccine, two with an onset within 3 days following vaccination. Orchitis is a common complication of mumps infection, particularly in post-pubertal males, and is also recognized as a very rare complication of mumps vaccination. These cases, discussed together with a comprehensive review of the existing literature regarding post-vaccine orchitis, highlight uncertainty regarding the pathogenesis of post-vaccine orchitis.
Copyright 2010 Elsevier Ltd. All rights reserved.
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