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. 2010 Oct;18(5):253-60.
doi: 10.1007/s10787-009-0028-6. Epub 2010 Jan 20.

Anti-inflammatory effect of Acacia visco extracts in animal models

Ana María Pedernera  1 , Teresita Guardia, Carola Elisa Guardia Calderón, Alejandra Ester Rotelli, Nadir Ernesto de la Rocha, José Roberto Saad, María Alejandra Lopez Verrilli, Susana Garcia Aseff, Lilian Eugenia Pelzer
Affiliations

Anti-inflammatory effect of Acacia visco extracts in animal models

Ana María Pedernera et al. Inflammopharmacology. 2010 Oct.

Abstract

The aqueous and organic extracts of Acacia visco Lor. Ap Griseb (Fabaceae) were tested for anti-inflammatory activity in experimental models in rat. Besides, the free-radical scavenging capacity of extracts from A. visco was determined. The extracts revealed anti-inflammatory effect against carrageenan-induced oedema, phospholipase A(2)-induced oedema, cotton pellet-induced granuloma and they did not show acute toxic effect. Among the class of compounds characterized from A. visco leaves, the triterpenoid 20(29)-lupen-3β-ol (lupeol), 12-ursen-3β-ol (α-amyrin) and 12-oleanen-3β-ol (β-amyrin) may be mainly responsible for the pharmacological activities.

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