Mediators of ocular angiogenesis
- PMID: 20090210
- PMCID: PMC3306772
- DOI: 10.1007/s12041-009-0068-0
Mediators of ocular angiogenesis
Abstract
Angiogenesis is the formation of new blood vessels from pre-existing vasculature. Pathologic angiogenesis in the eye can lead to severe visual impairment. In our review, we discuss the roles of both pro-angiogenic and anti-angiogenic molecular players in corneal angiogenesis, proliferative diabetic retinopathy, exudative macular degeneration and retinopathy of prematurity, highlighting novel targets that have emerged over the past decade.
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