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. 2010 Jan 20;2010(1):CD007894.
doi: 10.1002/14651858.CD007894.pub2.

Roselle for hypertension in adults

Chetta Ngamjarus  1 , Porjai Pattanittum, Charoonsak Somboonporn
Affiliations

Roselle for hypertension in adults

Chetta Ngamjarus et al. Cochrane Database Syst Rev. .

Update in

  • Roselle for hypertension in adults.
    Pattanittum P, Ngamjarus C, Buttramee F, Somboonporn C. Pattanittum P, et al. Cochrane Database Syst Rev. 2021 Nov 27;11(11):CD007894. doi: 10.1002/14651858.CD007894.pub3. Cochrane Database Syst Rev. 2021. PMID: 34837382 Free PMC article.

Abstract

Background: Hypertension is considered a serious health problem worldwide. Controlling and lowering blood pressure have a significant benefit to the hypertensive patients because hypertension is a risk factor for stroke, heart disease and cardiovascular disease. A tropical plant called Roselle, or Red Sorrel in English-speaking countries, has been used both as a thirst-quenching drink and for medical purposes.

Objectives: To explore the effect of Roselle on blood pressure in hypertensive adult patients.

Search strategy: The following databases were searched (Date of most recent search was September 2009): - Cochrane Database of Systematic Reviews (2nd Quarter 2009) - DARE (2nd Quarter 2009) - Ovid MEDLINE (1950 to Present with Daily Update) - EMBASE (1980 to 2009 Week 22) - AMED (1985 to May 2009) - EBSCO CINAHL - BIOSIS (1969 to 2008) - AGRICOLA (1970 to May 2009) - Food Science and Technology Abstract (1969 to 2009 June Week 1) - International Pharmaceutical Abstracts - International Bibliographic Information on Dietary Supplements - Clinical Trials.gov and Current Controlled Trials - OpenSIGLE - Hand searching of journals - ISI Web of Knowledge

Selection criteria: We sought randomised control trials (RCTs) evaluating use of any forms of Roselle with placebo or no treatment in hypertensive patients. Change in trough and/or peak systolic and diastolic blood pressure were primary outcomes. Secondary outcomes were withdrawals due to adverse effects, change of pulse pressure and change of heart rate.

Data collection and analysis: Two review authors (C Ngamjarus, CN and P Pattanittum, PP) independently scanned titles and abstracts, as well as independently screened the full reports of the potentially relevant studies. At each stage, the results were compared and disagreements were solved by discussion.

Main results: No studies were identified that met the inclusion criteria. However, one abstract of an ongoing study is likely to meet the inclusion criteria, when completed.

Authors' conclusions: There is insufficient evidence to support the benefit of Roselle for either controlling or lowering blood pressure in patients with hypertension. Based on the information of this review, there is a clear need to develop well-designed studies to assess the efficacy of Roselle on hypertensive patients.

PubMed Disclaimer

Conflict of interest statement

P Pattanittum: none known.

C Ngamjarus: none known.

F Buttramee: none known.

C Somboonporn: none known.

Figures

1
1
study flow diagram.
2
2
Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
3
3
Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
4
4
Figure 4 Searching other resources (2.1) to (2.5); using Thai language
1.1
1.1. Analysis
Comparison 1: Roselle extract versus placebo, Outcome 1: Change in systolic blood pressure (mmHg) at week 8
1.2
1.2. Analysis
Comparison 1: Roselle extract versus placebo, Outcome 2: Change in diastolic blood pressure (mmHg) at week 8
See this image and copyright information in PMC

References

References to studies included in this review

Sarbini 2019 {published data only}
    1. Sarbini DWI, Huriyati EMY, Sadewa H, Wahyuningsih MSH. The effect of rosella (Hibiscus sabdariffa linn) on insulin resistance in patients with type 2 diabetes mellitus: a randomized clinical trial. International Journal of Pharmaceutical Research 2019;11:547-57.

References to studies excluded from this review

Abubakar 2019 {published data only}
    1. Abubakar SM, Ukeyima MT, Spencer JPE, Lovegrove JA. Acute effects of hibiscus sabdariffa calyces on postprandial blood pressure, vascular function, blood lipids, biomarkers of insulin resistance and inflammation in humans. Nutrients 2019;11(2):5. - PMC - PubMed
Aroonsiriwatana 2010 {published data only}
    1. Aroonsiriwatana S. The Effects of Roselle (Hibiscus Sabdariffa) and Stevia (Stevia Rebaudiana) on Hypertension in Patients with Type 2 Diabetes at King Chulalongkorn Memorial Hospital [Masters thesis]. Bangkok (TH): Chulalongkorn University, 2010.
Asgary 2016 {published data only}
    1. Asgary S, Soltani R, Zolghadr M, Keshvari M, Sarrafzadegan N. Evaluation of the effects of roselle (Hibiscus sabdariffa L.) on oxidative stress and serum levels of lipids, insulin and hs-CRP in adult patients with metabolic syndrome: a double-blind placebo-controlled clinical trial. Journal of Complementary & Integrative Medicine 2016;13(2):175-80. - PubMed
Boix‐Castejon 2017 {published data only}
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Hadi 2017 {published data only}
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IRCT201310089662N8 {published data only}
    1. IRCT201310089662N8. Evaluation of the effects of sour tea on lipid profile, insulin resistance, oxidative stress, and inflammatory markers in adult patients with metabolic syndrome. www.who.int/trialsearch/Trial2.aspx?TrialID=IRCT201310089662N8 (first received 4 December 2013).
IRCT2014041510826N8 {published data only}
    1. IRCT2014041510826N8. Effect of Hibiscus subdariffa on albuminuria, total antioxidant capacity, hypertension and hs-CRP in patient with diabetic nephropathy. www.who.int/trialsearch/Trial2.aspx?TrialID=IRCT2014041510826N8 (first received 4 December 2013).
Jalalyazdi 2019 {published data only}
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Kafeshani 2017 {published data only}
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Marhuenda 2021 {published data only}
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McKay 2008 {published data only}
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Nwachukwu 2015 {published data only}
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Nwachukwu 2015a {published data only}
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Tangkomsaengtong 2020 {published data only}
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Thanasatirakul 2015 {published data only}
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Wiruttanapornkul 2012 {published data only}
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Yusni 2020 {published data only}
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References to studies awaiting assessment

Al‐Anbaki 2021 {published data only}
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References to other published versions of this review

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