Varicella vaccination in pediatric kidney and liver transplantation
- PMID: 20091941
- DOI: 10.1111/j.1399-3046.2009.01204.x
Varicella vaccination in pediatric kidney and liver transplantation
Abstract
Reports about efficacy and safety of live-virus attenuated vaccines in patients before and after transplantation are mainly based on small patient numbers, making general recommendations for this patient population difficult. Children and adults as well as their close relatives and contact persons should be preferably immune to VZV before solid organ transplantation to avoid VZV-associated complications, thus making VZV vaccination necessary in susceptible individuals. The following literature review focused on efficacy and safety of VZV vaccination in pediatric kidney and liver transplant recipients. Review of literature also revealed that in all pediatric transplant candidates, humoral and cellular immunity against VZV should be consistently monitored to assess waning immunity under immunosuppressive treatment. This approach is desirable to estimate the risk of severe varicella disease after exposure in these patients.
(c) 2009 John Wiley & Sons A/S.
Similar articles
-
Varicella zoster virus serostatus before and after kidney transplantation, and vaccination of adult kidney transplant candidates.Transplant Proc. 2006 Dec;38(10):3418-9. doi: 10.1016/j.transproceed.2006.10.090. Transplant Proc. 2006. PMID: 17175291
-
Effectiveness of live varicella vaccine.Expert Opin Biol Ther. 2004 Feb;4(2):199-216. doi: 10.1517/14712598.4.2.199. Expert Opin Biol Ther. 2004. PMID: 14998778 Review.
-
Humoral and cellular response after varicella vaccination in VZV IgG seronegative kidney transplant candidates.Vaccine. 2017 Jan 3;35(1):71-76. doi: 10.1016/j.vaccine.2016.11.043. Epub 2016 Nov 26. Vaccine. 2017. PMID: 27899225
-
Attenuated varicella virus vaccine in children with renal transplants.Pediatr Nephrol. 1994 Apr;8(2):190-2. doi: 10.1007/BF00865476. Pediatr Nephrol. 1994. PMID: 8018498
-
α Herpes Virus Infections Among Renal Transplant Recipients.Semin Nephrol. 2016 Sep;36(5):344-350. doi: 10.1016/j.semnephrol.2016.05.011. Semin Nephrol. 2016. PMID: 27772619 Review.
Cited by
-
Non-viral infections in children after renal transplantation.Pediatr Nephrol. 2012 Sep;27(9):1465-76. doi: 10.1007/s00467-011-2099-z. Epub 2012 Feb 9. Pediatr Nephrol. 2012. PMID: 22318475 Free PMC article. Review.
-
Minimizing infection risks after paediatric organ transplants: Advice for practitioners.Paediatr Child Health. 2013 Mar;18(3):143-54. Paediatr Child Health. 2013. PMID: 24421679 Free PMC article.
-
Live virus vaccines in transplantation: friend or foe?Curr Infect Dis Rep. 2015 Apr;17(4):472. doi: 10.1007/s11908-015-0472-y. Curr Infect Dis Rep. 2015. PMID: 25870140
-
Psychiatric issues in pediatric organ transplantation.Child Adolesc Psychiatr Clin N Am. 2010 Apr;19(2):285-300, viii-ix. doi: 10.1016/j.chc.2010.02.002. Child Adolesc Psychiatr Clin N Am. 2010. PMID: 20478500 Free PMC article. Review.
-
Aciclovir and varicella-zoster-immunoglobulin in solid-organ transplant recipients.Pediatr Nephrol. 2011 May;26(5):663-73. doi: 10.1007/s00467-010-1666-z. Epub 2010 Nov 15. Pediatr Nephrol. 2011. PMID: 21076967 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical