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Case Reports
. 2010 Sep;11(9):700-3.
doi: 10.2459/JCM.0b013e328332e873.

Capecitabine cardiac toxicity presenting as effort angina: a case report

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Case Reports

Capecitabine cardiac toxicity presenting as effort angina: a case report

Chiara Lestuzzi et al. J Cardiovasc Med (Hagerstown). 2010 Sep.

Abstract

We report a case of capecitabine-induced cardiotoxicity (effort angina) in a woman with metastatic breast carcinoma. Due to cancer progression, rechallenge of therapy with capecitabine was attempted, using several strategies in order to prevent cardiotoxicity. The most (even if not fully) effective strategy was reducing capecitabine dosage together with nitrates, calcium-channel blockers and trimetazidine therapy.

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