Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2010 May;17(5):373-4.
doi: 10.1038/cgt.2009.90. Epub 2010 Jan 22.

Neuroblastoma-specific expression of potential therapeutics cannot be achieved using a promoter region of the NCX (TLX2) gene

A Tivnan, R L Stallings
Comment

Neuroblastoma-specific expression of potential therapeutics cannot be achieved using a promoter region of the NCX (TLX2) gene

A Tivnan et al. Cancer Gene Ther. 2010 May.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Luciferase expression in NCX1.7-luc-transfected cell lines 48 hours after transfection. All data was normalised to pGL2-basic empty vector (encoding the luciferase gene devoid of a promoter region) transfected cells. pMIR-Report vector (Applied Biosystems) was used as a positive control for successful transfection in each of the cell lines tested (data not shown). All expression values are relative to HEK293-transfected cells, set as 1.0.
See this image and copyright information in PMC

Comment on

Similar articles

See all similar articles

Cited by

References

    1. Brodeur GM. Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer. 2003;3(3):203–216. - PubMed
    1. Narita M, Bahar R, Hatano M, Kang MM, Tokuhisa T, Goto S, Saisho H, Sakiyama S, Tagawa M. Tissue-specific expression of a suicide gene for selective killing of neuroblastoma cells using a promoter region of the NCX gene. Cancer Gene Ther. 2001;8(12):997–1002. - PubMed
    1. Rao MK, Wilkinson MF. Tissue-specific and cell type-specific RNA interference in vivo. Nat Protoc. 2006;1(3):1494–1501. - PubMed
    1. Yang W, Paschen W. Conditional gene silencing in mammalian cells mediated by a stress-inducible promoter. Biochem. Biophys. Res. Commun. 2008;365(3):521–527. - PubMed
    1. Borghini S, Bachetti T, Fava M, Di Duca M, Cargnin F, Fornasari D, Ravazzolo R, Ceccherini I. The TLX2 homeobox gene is a transcriptional target of PHOX2B in neural-crest-derived cells. Biochem J. 2006;395(2):355–361. - PMC - PubMed