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. 1977 Nov;74(11):4982-5.
doi: 10.1073/pnas.74.11.4982.

Sequence arrangement of the 5' ends of simian virus 40 16S and 19S mRNAs

M T Hsu, J Ford

Sequence arrangement of the 5' ends of simian virus 40 16S and 19S mRNAs

M T Hsu et al. Proc Natl Acad Sci U S A. 1977 Nov.

Abstract

Electron microscopic examination of molecular hybrids between simian virus 40 DNA, that had been cleaved with EcoRI and then digested with exonuclease III, and either 16S or 19S mRNA produced late during the viral infection cycle indicated that each of these mRNAs contained a 5'-terminal "leader" sequence that was encoded in the viral genome at about map position 0.71-0.75. Hybridization of each of these mRNAs to viral DNA immobilized on nitrocellulose filters supported the electron microscopic observations.

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References

    1. J Mol Biol. 1964 Jul;9:46-69 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Sep;74(9):3686-90 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Feb;74(2):496-500 - PubMed
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    1. Cell. 1977 Sep;12(1):9-21 - PubMed

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