First efficient synthesis of fluorinated glycidic esters from ketones
- PMID: 20095572
- DOI: 10.1021/ol902903v
First efficient synthesis of fluorinated glycidic esters from ketones
Abstract
Treatment of various ketones with ethyl dibromofluoroacetate in the presence of diethylzinc and dimethylaminoethanol or triphenylphosphine provides rapid access to corresponding fluorinated glycidic esters. Simplified workup allowed first characterization of these compounds.
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