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. 2010 Jan;24(1):39-48.
doi: 10.1089/apc.2009.0152.

Prevalence and patient awareness of medical comorbidities in an urban AIDS clinic

Jeffrey J Weiss  1 , Georgina Osorio, Elizabeth Ryan, Sue M Marcus, Dawn A Fishbein
Affiliations

Prevalence and patient awareness of medical comorbidities in an urban AIDS clinic

Jeffrey J Weiss et al. AIDS Patient Care STDS. 2010 Jan.

Abstract

Mortality in HIV-positive persons is increasingly due to non-HIV-related medical comorbidities. There are limited data on the prevalence and patient awareness of these comorbid conditions. Two hundred subjects at an urban HIV clinic were interviewed in 2005 to assess their awareness of 15 non-HIV-related medical comorbidities, defined as medical problems that are neither AIDS-defining by standard definitions, nor a direct effect of immune deficiency. Medical charts were subsequently reviewed to establish prevalence and concordance between self-report and chart documentation. Eighty-four percent of subjects self-reported at least 1 of 15 medical comorbidities and 92% had at least 1 condition chart-documented. The top 5 chart-documented conditions were hepatitis C (51.5%), pulmonary disease (28.5%), high blood pressure (27%), high cholesterol (24.5%), and obesity (22.5%). In multivariate analysis, higher number of non-HIV-related medical comorbidities was associated with older age, female gender, and intravenous drug use as route of HIV transmission. Across self-reported non-HIV-related medical comorbidities, the absolute concordance rate ranged from 67% to 96%, the sensitivity ranged from 0% to 79%; the positive predictive value ranged from 0% to 100%. While the vast majority of largely urban minority HIV-positive subjects were diagnosed with non-HIV-related medical comorbidities, there is significant room for improvement in patient awareness. In order to help patients optimally access and adhere to medication and medical care for these non-HIV-related medical comorbidities, interventions and educational campaigns to improve patient awareness that take cultural background, literacy, and educational level into account should be developed, implemented, and evaluated.

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Figures

FIG. 1.
FIG. 1.
Prevalence of self-reported and chart-documented comorbid conditions.
FIG. 2.
FIG. 2.
Observed mean number of chart comorbidities by age, gender, and route of HIV transmission.
See this image and copyright information in PMC

References

    1. Sackoff JE. Hanna DB. Pfeiffer MR. Torian LV. Causes of death among persons with AIDS in the era of highly active antiretroviral therapy: New York City. Ann Intern Med. 2006;145:397–406. - PubMed
    1. Crum NF. Riffenburgh RH. Wegner S, et al. Comparisons of causes of death and mortality rates among HIV-infected persons: Analysis of the pre-, early, and late HAART (highly active antiretroviral therapy) eras. J Acquir Immune Defic Syndr. 2006;41:194–200. - PubMed
    1. French AL. Gawel SH. Hershow R, et al. Trends in Mortality and Causes of Death Among Women With HIV in the United States: A 10-Year Study. J Acquir Immune Defic Syndr. 2009;51:399–406. - PMC - PubMed
    1. Bica I. McGovern B. Dhar R, et al. Increasing mortality due to end-stage liver disease in patients with human immunodeficiency virus infection. Clin Infect Dis. 2001;32:492–497. - PubMed
    1. Lacombe K. Pacanowski J. [HIV infection and comorbidities] Rev Prat. 2006;56:995–1004. - PubMed

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