Review
. 2010 Apr;31(4):141-2; author reply 142-3.
doi: 10.1016/j.tips.2009.12.006.
Epub 2010 Jan 22.
Lessons from the rotenone model of Parkinson's disease
- PMID: 20096940
- PMCID: PMC2846992
- DOI: 10.1016/j.tips.2009.12.006
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Review
Lessons from the rotenone model of Parkinson's disease
Trends Pharmacol Sci.
2010 Apr.
No abstract available
Comment on
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Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?Trends Pharmacol Sci. 2009 Sep;30(9):475-83. doi: 10.1016/j.tips.2009.06.005. Epub 2009 Sep 2. Trends Pharmacol Sci. 2009. PMID: 19729209 Review.
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References
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- Cicchetti F, et al. Environmental toxins and Parkinson’s disease: what have we learned from pesticide-induced animal models? Trends Pharmacol Sci. 2009;30:475–483. - PubMed
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- Heikkila RE, et al. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity. Neurosci Lett. 1985;62:389–394. - PubMed
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- Ferrante RJ, et al. Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra. Brain Res. 1997;753:157–162. - PubMed
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- Betarbet R, et al. Chronic systemic pesticide exposure reproduces features of Parkinson’s disease. Nat Neurosci. 2000;3:1301–1306. - PubMed
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- Schmidt WJ, Alam M. Controversies on new animal models of Parkinson’s disease pro and con: the rotenone model of Parkinson’s disease (PD) J Neural Transm Suppl. 2006:273–276. - PubMed
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