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Review
. 2010 May 17;584(10):2102-11.
doi: 10.1016/j.febslet.2010.01.037. Epub 2010 Jan 26.

Chloride channels of intracellular membranes

John C Edwards  1 , Christina R Kahl
Affiliations
Review

Chloride channels of intracellular membranes

John C Edwards et al. FEBS Lett. .

Abstract

Proteins implicated as intracellular chloride channels include the intracellular ClC proteins, the bestrophins, the cystic fibrosis transmembrane conductance regulator, the CLICs, and the recently described Golgi pH regulator. This paper examines current hypotheses regarding roles of intracellular chloride channels and reviews the evidence supporting a role in intracellular chloride transport for each of these proteins.

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