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Review
. 2010 Feb;26(1):85-9.
doi: 10.1007/s12264-010-0604-1.

Research advancement in immunopathogenesis of myasthenia gravis

Sha Huang  1 , Li-Ming Tan
Affiliations
Review

Research advancement in immunopathogenesis of myasthenia gravis

Sha Huang et al. Neurosci Bull. 2010 Feb.

Abstract
in English, Chinese

Myasthenia gravis (MG) is an autoimmune neuromuscular junction disease mediated by antibodies against the acetylcholine receptor (AChR). The etiology and immunopathogenesis of MG remain unclear. Recent research has shown the involvement of autoantibodies, lymphocytes, cytokines and chemokines, in the pathogenesis of MG. Systematic factors are also demonstrated, such as inheritance and endocrine. This review indicates the research development in immunopathogenesis of MG.

症肌无力是一种由抗乙酰胆碱受体的抗体介导的神经肌肉接头处的自身免疫病。 其发病机制尚未阐明。 自身抗体、 淋巴细胞免疫调节紊乱、 细胞因子表达失衡及系统因素在重症肌无力的发病机制中均起重要作用。 本综述旨在探讨重症肌无力的免疫学发病机制。

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