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Case Reports
. 2009 Nov-Dec;64(6):517-9.
doi: 10.1179/acb.2009.088.

Haemolytic anaemia caused by piperacillin-tazobactam

I Dapper  1 , M Nauwynck, D Selleslag, M Hidajat, M Bourgeois, P Martens, A Wilmer
Affiliations
Case Reports

Haemolytic anaemia caused by piperacillin-tazobactam

I Dapper et al. Acta Clin Belg. 2009 Nov-Dec.

Abstract

We report a case of haemolytic due to the use of piperacillin-tazobactam in a 50-year-old woman. Since 2002 4 other cases were reported. Either the presence of piperacillin as tazobactam can induce haemolysis. In all cases discontinuating the drugs resolves the haemolysis. Although drug-induced haemolytic anaemia due to piperacillin-tazobactam is rare, the common use of this antibioticum in the critical care setting should alert the physician as a possible culprit in cases of haemolytic anaemia.

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