Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Feb;33(2):442-9.
doi: 10.2337/dc09-0749.

Cardiovascular disease in type 2 diabetes from population to man to mechanisms: the Kelly West Award Lecture 2008

Affiliations

Cardiovascular disease in type 2 diabetes from population to man to mechanisms: the Kelly West Award Lecture 2008

Markku Laakso. Diabetes Care. 2010 Feb.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Different approaches in studies of cardiovascular complications in type 2 diabetes.
Figure 2
Figure 2
Incidence per 1,000 person-years and Cox model hazard ratio for CHD death (adjusted for age, area of residence, and sex) during the 18-year follow-up according to the presence of diabetes and prior evidence of MI in 1,373 nondiabetic and 1,059 diabetic subjects. Adapted from ref. .
Figure 3
Figure 3
Relative risk of CVD in normoglycemia, pre-diabetes, and type 2 diabetes.
Figure 4
Figure 4
Parallel insulin-signaling pathways mediating metabolic and vascular effects in peripheral tissues. eNOS, endothelial nitric oxide synthase; ET-1, endothelin 1. Modified from ref. .
Figure 5
Figure 5
The “common soil” hypothesis of diabetes complications.

Similar articles

Cited by

References

    1. Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature 2001; 414: 782– 787 - PubMed
    1. Amos A, McCarty D, Zimmet P. The rising global burden of diabetes and its complications: estimates and projections to the year 2010. Diabet Med 1997; 14: S1– S85 - PubMed
    1. Laakso M. Cardiovascular disease in type 2 diabetes: challenge for treatment and prevention. J Intern Med 2001; 249: 225– 235 - PubMed
    1. Laakso M, Lehto S. Epidemiology of macrovascular disease in diabetes. Diabetes Rev 1997; 5: 294– 315
    1. Miettinen H, Lehto S, Salomaa V, Mähönen M, Niemelä M, Haffner SM, Pyörälä K, Tuomilehto J. Impact of diabetes on mortality after the first myocardial infarction: the FINMONICA Myocardial Infarction Register Study Group. Diabetes Care 1998; 21: 69– 75 - PubMed

MeSH terms