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Editorial
. 2010 Feb;33(2):453-5.
doi: 10.2337/dc09-1902.

GLP-1-based therapy for diabetes: what you do not know can hurt you

Editorial

GLP-1-based therapy for diabetes: what you do not know can hurt you

Peter C Butler et al. Diabetes Care. 2010 Feb.
No abstract available

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Figures

Figure 1
Figure 1
Theoretical model to explain currently available observations with increased risks for pancreatic cancer in individuals with obesity and type 2 diabetes, a risk that is decreased by metformin treatment and theoretically may be increased by GLP-1–based treatment.

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    1. Drucker DJ, Sherman SI, Gorelick FS, Bergenstal RM, Sherwin RS, Buse JB. Incretin-based therapies for the treatment of type 2 diabetes: evaluation of the risks and benefits. Diabetes Care 2010; 33: 428– 433 - PMC - PubMed
    1. Holst JJ, Vilsbøll T, Deacon CF. The incretin system and its role in type 2 diabetes mellitus. Mol Cell Endocrinol 2009; 297: 127– 136 - PubMed
    1. Staels B, Fruchart JC. Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes 2005; 54: 2460– 2470 - PubMed
    1. Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, Skene AM, Tan MH, Lefèbvre PJ, Murray GD, Standl E, Wilcox RG, Wilhelmsen L, Betteridge J, Birkeland K, Golay A, Heine RJ, Korányi L, Laakso M, Mokán M, Norkus A, Pirags V, Podar T, Scheen A, Scherbaum W, Schernthaner G, Schmitz O, Skrha J, Smith U, Taton Jthe PROactive investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 2005; 366: 1279– 1289 - PubMed
    1. Home PD, Pocock SJ, Beck-Nielsen H, Curtis PS, Gomis R, Hanefeld M, Jones NP, Komajda M, McMurray JJRECORD Study Team. Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial. Lancet 2009; 373: 2125– 2135 - PubMed

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