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. 2010 Jul-Aug;24(4):572-7.
doi: 10.1111/j.1399-0012.2010.01208.x.

The impact of cytomegalovirus infection ≥1 year after primary renal transplantation

Barry J Browne  1 , Jo-Anne Young, Ty B Dunn, Arthur J Matas
Affiliations

The impact of cytomegalovirus infection ≥1 year after primary renal transplantation

Barry J Browne et al. Clin Transplant. 2010 Jul-Aug.

Abstract

We studied the impact of a first post-transplant cytomegalovirus (CMV) infection greater than one year after primary kidney transplantation. Risk factors for developing late CMV were acute rejection and donor-recipient CMV status. Of those developing late CMV, 35% were donor (D) positive, recipient (R) negative; however, 23% were D+R+, 22% D-R+, and 15% D-R-. Late CMV was associated with significantly decreased patient and graft survival.

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Figures

Fig. 1
Fig. 1
The impact of cytomegalovirus infection on actuarial patient and graft survival: (A) living donor (LD) graft survival; (B) deceased donor (DD) graft survival; (C) LD recipient survival; (D) DD recipient survival.
Fig. 2
Fig. 2
Actuarial recipient and death-censored graft survival after cytomegalovirus (CMV) diagnosis for early vs. late CMV infection: (A) living donor; (B) deceased donor.
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