Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Mar 15;26(6):851-2.
doi: 10.1093/bioinformatics/btq028. Epub 2010 Jan 26.

Easy retrieval of single amino-acid polymorphisms and phenotype information using SwissVar

Anaïs Mottaz  1 , Fabrice P A David, Anne-Lise Veuthey, Yum L Yip
Affiliations

Easy retrieval of single amino-acid polymorphisms and phenotype information using SwissVar

Anaïs Mottaz et al. Bioinformatics. .

Abstract

Summary: The SwissVar portal provides access to a comprehensive collection of single amino acid polymorphisms and diseases in the UniProtKB/Swiss-Prot database via a unique search engine. In particular, it gives direct access to the newly improved Swiss-Prot variant pages. The key strength of this portal is that it provides a possibility to query for similar diseases, as well as the underlying protein products and the molecular details of each variant. In the context of the recently proposed molecular view on diseases, the SwissVar portal should be in a unique position to provide valuable information for researchers and to advance research in this area.

Availability: The SwissVar portal is available at www.expasy.org/swissvar

Contact: anais.mottaz@isb-sib.ch; lina.yip@isb-sib.ch

Supplementary information: Supplementary data are available at Bioinformatics online.

PubMed Disclaimer

References

    1. David FP, Yip YL. SSMap: a new UniProt-PDB mapping resource for the curation of structural-related information in the UniProt/Swiss-Prot Knowledgebase. BMC Bioinformatics. 2008;9:391. - PMC - PubMed
    1. Lage K, et al. A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat. Biotechnol. 2007;25:309–316. - PubMed
    1. Mottaz A, et al. Mapping proteins to disease terminologies: from UniProt to MeSH. BMC Bioinformatics. 2008;9(Suppl. 5):S3. - PMC - PubMed
    1. Oti M, et al. Phenome connections. Trends Genet. 2008;24:103–106. - PubMed
    1. Robinson PN, et al. The Human Phenotype Ontology: a tool for annotating and analyzing human hereditary disease. Am. J. Hum. Genet. 2009;83:610–615. - PMC - PubMed

Publication types