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Comment
. 2010 Jan;122(1):198-200.
doi: 10.3810/pgm.2010.01.2115.

Reducing cardiac ischemic events in patients with ACS: prasugrel versus clopidogrel. Commentary

Scott Solomon  1 , James L Vacek
Affiliations
Comment

Reducing cardiac ischemic events in patients with ACS: prasugrel versus clopidogrel. Commentary

Scott Solomon et al. Postgrad Med. 2010 Jan.

Abstract

Prasugrel was associated with a statistically significant reduction in rates of cardiac ischemic events in patients with ACS who had undergone PCI. Rates of post-PCI death from cardiovascular causes, nonfatal MI, or nonfatal stroke were also significantly reduced with the use of prasugrel versus clopidogrel. Major bleeding was significantly increased with the use of prasugrel versus clopidogrel. Mortality did not differ significantly between the groups.

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  • Prasugrel versus clopidogrel in patients with acute coronary syndromes.
    Wiviott SD, Braunwald E, McCabe CH, Montalescot G, Ruzyllo W, Gottlieb S, Neumann FJ, Ardissino D, De Servi S, Murphy SA, Riesmeyer J, Weerakkody G, Gibson CM, Antman EM; TRITON-TIMI 38 Investigators. Wiviott SD, et al. N Engl J Med. 2007 Nov 15;357(20):2001-15. doi: 10.1056/NEJMoa0706482. Epub 2007 Nov 4. N Engl J Med. 2007. PMID: 17982182 Clinical Trial.

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