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Review
. 2010 Jan;47(1):97-103.
doi: 10.1053/j.seminhematol.2009.10.002.

Umbilical cord transplantation: epilogue

Hal E Broxmeyer  1
Affiliations
Review

Umbilical cord transplantation: epilogue

Hal E Broxmeyer. Semin Hematol. 2010 Jan.

Abstract

The field of cord blood transplantation has come a long way since the first transplant more than 20 years ago. Advancements in the field will require continuing efforts to better understand hematopoietic stem and progenitor cell function and engraftment. Cautious optimism is inherent in the potential relevance and applicability of nonhematopoietic stem and progenitor cell types found in cord blood, and induced pluripotent stem cells generated from cord blood cells. Rigorous investigations and close interactions between scientific and clinical investigators are required to translate human in vitro and animal in vivo findings into clinical utility.

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References

    1. Broxmeyer HE. Cord Blood Transplantation: A Mini Review Celebrating the 20th Anniversary of the First Cord Blood Transplant. The Hematologist. 2009 Jan/Feb;6(Issue 1):7. Publication of the American Society of Hematology.
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    1. Broxmeyer HE. Introduction: Past, present and future of cord blood transplantation. In: Broxmeyer HE, editor. Cellular Characteristics of Cord Blood and Cord Blood Transplantation. Amer. Assoc. Blood Banking.; 1997. pp. 1–11.

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