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. 2010;56(2):113-8.
doi: 10.1159/000277662. Epub 2010 Jan 29.

Passive smoke exposure and circulating carotenoids in the CARDIA study

Rachel Widome  1 , David R Jacobs Jr, Atsushi Hozawa, Femke Sijtsma, Myron Gross, Pamela J Schreiner, Carlos Iribarren
Affiliations

Passive smoke exposure and circulating carotenoids in the CARDIA study

Rachel Widome et al. Ann Nutr Metab. 2010.

Abstract

Background/aims: Our objective was to assess associations between passive smoke exposure in various venues and serum carotenoid concentrations.

Methods: CARDIA is an ongoing longitudinal study of the risk factors for subclinical and clinical cardiovascular disease. At baseline in 1985/1986, serum carotenoids were assayed and passive smoke exposure inside and outside of the home and diet were assessed by self-report. Our analytic sample consisted of 2,633 black and white non-smoking adults aged 18-30 years.

Results: Greater total passive smoke exposure was associated with lower levels of the sum of the three provitamin A carotenoids, alpha-carotene, beta-carotene, and beta-cryptoxanthin (-0.048 nmol/l per hour of passive smoke exposure, p = 0.001), unassociated with lutein/zeaxanthin, and associated with higher levels of lycopene (0.027 nmol/l per hour of passive smoke exposure, p = 0.010) after adjustment for demographics, diet, lipid profile, and supplement use. Exposure in both home and non-home spaces was also associated with lower levels of the provitamin A carotenoid index.

Conclusion: Cross-sectionally, in 1985/86, passive smoke exposure in various venues was associated with reduced levels of provitamin A serum carotenoids.

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References

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