Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Dec 24:3:121-4.
doi: 10.2174/1874325000903010121.

Effect of interlaminar epidural steroid injection in acute and subacute pain due to lumbar disk herniation: a randomized comparison of 2 different protocols

Affiliations

Effect of interlaminar epidural steroid injection in acute and subacute pain due to lumbar disk herniation: a randomized comparison of 2 different protocols

I D Gelalis et al. Open Orthop J. .

Abstract

In order to assess the efficacy of epidural steroid injections (ESI) in acute and subacute pain due to lumbar spine disk herniation, we conducted a randomized trial, comparing 2 different protocols. Fourty patients with radicular pain due to L4-L5 and L5-S1 disc herniation were assigned to receive either 3 consecutive ESI every 24 hours through a spinal catheter (group A) or 3 consecutive ESI every 10 days with an epidural needle (group B). All patients had improved Oswestry Disabilty Index (ODI) and the Visual Analog Scale (VAS) for pain scores at 1 month of follow-up compared to baseline, while no significant differences were observed between the 2 groups. The scores for group B were statistically significant lower at 2 months of follow-up compared to those of group A. The improvement in the scores of group B was continuous since the mean scores at 2 months of follow up were lower compared to the respective scores at 1 month. Protocol B (3 consecutive ESI every 10 days) was found more effective in the treatment of subacute pain compared to Protocol A (3 consecutive ESI every 24 hours) with statistically significant differences in the ODI and VAS scores at 2 months of follow-up.

Keywords: Low back pain; disk herniation; epidural injections.; lumbar spine; radicular pain.

PubMed Disclaimer

Figures

Fig. (1)
Fig. (1)
ODI values for protocols A and B.
Fig. (2)
Fig. (2)
VAS values for protocols A and B.

Similar articles

Cited by

References

    1. Papageorgiou AC, Croft PR, Ferry S, Jayson MI, Silman AJ. Estimating the prevalence of low back pain in the general population. Evidence from the South Manchester Back Pain Survey. Spine. 1995;20(17):1889–94. - PubMed
    1. Mulleman D, Mammou S, Griffoul I, Watier H, Goupille P. Pathophysiology of disc related sciatica. I- Evidence supporting a chemical component. Joint Bone Spine. 2006;73(3):270–7. - PubMed
    1. Takahashi N, Yabuki S, Aoki Y, Kikuchi S. Pathomechanisms of nerve root injury caused by disc herniation: An experimental study of mechanical compression and chemical irritation. Spine. 2003;28(5):435–41. - PubMed
    1. Abdi S, Datta S, Trescot AM, et al. Epidural steroids in the management of chronic spinal pain: A systematic review. Pain Physician. 2007;10(1):185–212. - PubMed
    1. Arden NK, Price C, Reading I, et al. WEST Study Group. A multicentre randomized controlled trial of epidural corticosteroid injections for sciatica: The WEST study. Rheumatology (Oxford) 2005;44(11):1399–406. - PubMed

LinkOut - more resources