Review
doi: 10.1039/b816679j.
Epub 2009 Aug 24.
Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents
Affiliations
- PMID: 20111769
- DOI: 10.1039/b816679j
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Review
Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents
Chem Soc Rev.
2010 Feb.
Abstract
In this tutorial review, an effort towards presentation of a comprehensive account of the recent developments on various kinds of artemisinin derivatives including artemisinin dimers, trimers and tetramers has been made and their efficacy towards malaria parasites and different cancer cells lines was compared with that of artemisinins, and various other anti-malarial and anti-cancer drugs. It is expected that this review will provide first-hand information on artemisinin chemistry to organic/medicinal chemists, and pharmacologists working on anticancer and anti-malarial drug development.
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