Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2010 Feb;25(2):330-2.
doi: 10.3346/jkms.2010.25.2.330. Epub 2009 Jan 26.

Inflammatory myofibroblastic tumor of the kidney misdiagnosed as renal cell carcinoma

Kwang Ho Ryu  1 , Chang Min Im, Myung Ki Kim, Dongdeuk Kwon, Kwangsung Park, Soo Bang Ryu, Chan Choi
Affiliations
Case Reports

Inflammatory myofibroblastic tumor of the kidney misdiagnosed as renal cell carcinoma

Kwang Ho Ryu et al. J Korean Med Sci. 2010 Feb.

Abstract

The inflammatory myofibroblastic tumor (IMT), also knowns as inflammatory pseuduotumor, is a soft tissue lesion of unknown etiology. In the urogenital tract, IMT mainly affects the urinary bladder or prostate, but rarely the kidney. It has been considered as a nonneoplastic reactive inflammatory lesion, but nowadays, it is regarded as a neoplasm due to its high recurrence rate and metastasis. We describe a case of a 61-yr-old woman that had originally been misdiagnosed as renal cell carcinoma, which was pathologically revealed to be an IMT.

Keywords: Granuloma, Plasma Cell; Inflammation; Kidney Neoplasms.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Magnetic resonance image demonstrates a 3.0×2.5 cm size solid mass with mildly enhancement on left kidney lower pole with a central necrotic portion.
Fig. 2
Fig. 2
Left kidney coronal opening specimen shows a well-circumscribed encapsulated mass measuring 2.7×2.8 cm size, involving the lower pole. The mass revealed areas of myxoid change necrosis, and cystic change.
Fig. 3
Fig. 3
Microscopic findings. (A) The low power appearance demonstrating a capsule of dense collagenous fibrous tissue and myxoid zone and inflammation with cellular zone consisting of spindle cells arranged in fascicles. (B) The area of myofibroblastic proliferation showing densely cellular fascicles. The tumor cells were potive for smooth muscle actin (C) and vimentin (D).
See this image and copyright information in PMC

References

    1. Brunn H. Two interesting benign lung tumors of contradictory histopathology; remarks on the necessity for maintaining chest tumor registry. J Thorac Surg. 1939;9:119–131.
    1. Young RH, Eble JN. Urol Surg Pathol Mosby-Year Book. 1997. Non-neoplastic disorders of the urinary bladder; pp. 166–214.
    1. Larbcharoensub N, Chobpradit N, Kijvikai K, Chalermsanyakorn P. Primary renal inflammatory myofibroblastic tumor. Urol Int. 2006;76:94–96. - PubMed
    1. Coffin CM, Watterson J, Priest JR, Dehner LP. Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor): a clinicopathologic and immunohistochemical study of 84 cases. Am J Surg Pathol. 1995;19:859–872. - PubMed
    1. Kapusta LR, Weiss MA, Ramsay J, Lopez-Beltran A, Srigley JR. Inflammatory myofibroblastic tumors of the kidney: a clinicopathologic and immunohistochemical study of 12 cases. Am J Surg Pathol. 2003;27:658–666. - PubMed

Publication types