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. 2009 Dec;4(12):1701-6.

The cytotoxic properties of natural coumarins isolated from roots of Ferulago campestris (Apiaceae) and of synthetic ester derivatives of aegelinol

Sergio Rosselli  1 , Antonella Maria Maggio, Nicoletta Faraone, Vivienne Spadaro, Susan L Morris-Natschke, Kenneth F Bastow, Kuo-Hsiung Lee, Maurizio Bruno
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  • PMID: 20120111

The cytotoxic properties of natural coumarins isolated from roots of Ferulago campestris (Apiaceae) and of synthetic ester derivatives of aegelinol

Sergio Rosselli et al. Nat Prod Commun. 2009 Dec.

Abstract

Grandivittin (1), agasyllin (2), aegelinol benzoate (3) and felamidin (20), four natural coumarins isolated from Ferulago campestris, and several synthetic ester derivatives of aegelinol (4) were tested against four tumor cell lines. Some of them were shown to be marginally cytotoxic against the A549 lung cancer cell line.

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