Experience of clomiphene use in a district general hospital

Abstract

Clomiphene citrate (CC) has been widely used for ovulation induction since the 1960s, due to its ease of administration and minimal side-effects. We conducted a retrospective study of 565 women who attended the infertility clinic at a district general hospital (Victoria Hospital, Kirkcaldy) between January 2004 and October 2008. The database was analysed for age, pregnancy rates, type of infertility and pregnancy outcomes. The conception rate with clomiphene citrate was 25%. The drug was well tolerated in 97.5% of women. The miscarriage rate with CC was 4.3%. We believe that these data give useful insights on CC therapy to gynaecologists involved in infertility clinics in a district general hospital setting.