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Review
. 2010 Jan-Feb;1799(1-2):55-61.
doi: 10.1016/j.bbagrm.2009.11.013.

In vivo modulation of HMGA2 expression

Hena R Ashar  1 , Roland A Chouinard Jr, Madhavi Dokur, Kiran Chada
Affiliations
Review

In vivo modulation of HMGA2 expression

Hena R Ashar et al. Biochim Biophys Acta. 2010 Jan-Feb.

Abstract

While the biochemical role of the HMGA proteins has largely been elucidated in tissue culture, the majority of the insight as to their physiological functions in the processes of proliferation and development has been established in animal models of overexpression (transgenic) and null mice (knockouts). An emphasis has been placed on the HMGA2 studies which have defined its critical role in mesenchymal proliferation and differentiation.

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