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. 2010 Jan;29(1):1-10.
doi: 10.1016/j.healun.2009.10.009.

Second INTERMACS annual report: more than 1,000 primary left ventricular assist device implants

James K Kirklin  1 , David C Naftel, Robert L Kormos, Lynne W Stevenson, Francis D Pagani, Marissa A Miller, Karen L Ulisney, J Timothy Baldwin, James B Young
Affiliations

Second INTERMACS annual report: more than 1,000 primary left ventricular assist device implants

James K Kirklin et al. J Heart Lung Transplant. 2010 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Actuarial survival by device type. Patients are censored at the time of transplantation or device explant for recovery.The error bars represent 70% confidence intervals. LVAD, left ventricular assist device; Bi-VAD, biventricular assist device; RVAD, right ventricular assist device; TAH, total artificial heart.
Figure 2
Figure 2
Actuarial and parametric survival for the 1092 patients undergoing primary LVAD implant. Patients are censored at transplant or device explant for recovery. The dashed lines represent the 70% confidence limits. The hazard function (instantaneous risk of death) is depicted by the lower curve.
Figure 3
Figure 3
Actuarial survival stratified by INTERMACS level at implant. The depiction is as in Figure 1.
Figure 4
Figure 4
Actuarial survival stratified by device strategy at time of implant. The depiction is as in Figure 1. BTT, Bridge-to-Transplantation; BTC, Bridge- to-Candidacy; DT, Destination Therapy.
Figure 5
Figure 5
Competing outcomes depiction for primary LVADs with Bridge-to-Transplant (BTT) as the strategy at time of implant. At any time point during followup, the sum of the percents of all outcomes equals 100%.
Figure 6
Figure 6
Competing outcomes analyses for primary LVAD patients with bridge-to-candidacy (BTC) as initial strategy at time of implant. The depiction is as in Figure 5.
Figure 7
Figure 7
Primary LVAD patients with Destination Therapy (DT) as initial strategy at time of implant. The depiction is as in Figure 5.
Figure 8
Figure 8
Bar graph depicting the number of implants for each 6-month interval since the beginning of INTERMACS prospective data collection, divided between pulsatile pumps (Blue) and continuous flow pumps (Red). Note that the initial bar includes some additional patients implanted between June 23 and July 1, 2006, and that the patients implanted between January 1 and March 31, 2009 are not included in this depiction.
Figure 9
Figure 9
Actuarial survival following primary LVAD implant with an initial strategy of either Bridge-to-Transplant (BTT) or Bridge-to-Candidacy (BTC) strategy, stratified by pulsatile vs. continuous flow pumps. The depiction is as in Figure 1.
See this image and copyright information in PMC

References

    1. Kirklin JK, Naftel DC, Stevenson LW, Kormos RL, Pagani FD, Miller MA, Ulisney K, Young JB. INTERMACS: Database for Durable Devices for Circulatory Support: First Annual Report. JHLT. 2008;27(10):1065–1072. - PubMed
    1. Rose EA, Moskowitz AJ, Packer M, Sollano JA, Williams DL, Tierney AR, Heitjan DF, Meier P, Ascheim DD, Levitan RG, Weinberg AD, Stevenson LW, Shapiro PA, Lazar RM, Watson JT, Goldstein DJ, Gelijns AC. The REMATCH trial: rationale, design, and end points. Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure. Ann Thorac Surg. 1999;67(3):723–30. - PubMed
    1. Warner-Strvenson Lynne, Kirklin James K, Pagani Francis D, Young James B, Jessup Mariell, Miller Leslie, Kormos Robert L, Naftel David C, Ulisney Karen, Desvigne-Nickens Patrice. INTERMACS Profiles of Advanced Heart Failure: First Definition. J Heart Lung Transp. 2009;28(6):535–41. - PubMed

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