[Treatment of infiltrating nonmetastatic bladder cancers in elderly patients]
- PMID: 20123498
- DOI: 10.1016/S1166-7087(09)73360-3
[Treatment of infiltrating nonmetastatic bladder cancers in elderly patients]
Abstract
Total cystectomy is the reference treatment for infiltrating nonmetastatic bladder cancers. With the progress in anesthesia and postoperative intensive care, this treatment can be applied to a population of elderly subjects provided there is a strict oncological and geriatric evaluation of the patient. Recent series reporting total cystectomies in subjects over 75 years of age report comparable morbidity and mortality rates to the general population. Strategies to preserve the vesical reservoir can be indicated in selected cases. Their objectives are to guarantee local control and follow-up identical to radical cystectomy, while preserving a functional bladder and good quality of life. The strategies including transurethral resection with radiochemotherapy are analyzed. Thus, with multidisciplinary consensus and adapted management, elderly patients with significant comorbidities should not be automatically excluded from access to effective treatment of these cancers.
(c) 2009 Elsevier Masson SAS. All rights reserved.
Similar articles
-
Bladder-sparing therapy for muscle-infiltrating bladder cancer.Nat Clin Pract Urol. 2008 Jul;5(7):368-75. doi: 10.1038/ncpuro1145. Epub 2008 Jun 17. Nat Clin Pract Urol. 2008. PMID: 18560383 Review.
-
Bladder preservation: optimizing radiotherapy and integrated treatment strategies.BJU Int. 2008 Nov;102(9 Pt B):1345-53. doi: 10.1111/j.1464-410X.2008.07981.x. BJU Int. 2008. PMID: 19035903 Review.
-
The value of bladder-conserving strategies in muscle-invasive bladder carcinoma compared with radical surgery.Curr Opin Urol. 2007 Sep;17(5):358-62. doi: 10.1097/MOU.0b013e3282c4afa0. Curr Opin Urol. 2007. PMID: 17762631 Review.
-
Conservative treatment of invasive bladder carcinoma by transurethral resection, protracted intravenous infusion chemotherapy, and hyperfractionated radiotherapy: long term results.Cancer. 2004 Dec 1;101(11):2540-8. doi: 10.1002/cncr.20654. Cancer. 2004. PMID: 15481058 Clinical Trial.
-
Radiochemotherapy after transurethral resection is an effective treatment method in T1G3 bladder cancer.Anticancer Res. 2005 May-Jun;25(3A):1623-8. Anticancer Res. 2005. PMID: 16033071
Cited by
-
Challenging treatment decision-making in older urologic cancer patients.World J Urol. 2014 Apr;32(2):299-308. doi: 10.1007/s00345-013-1158-4. Epub 2013 Aug 30. World J Urol. 2014. PMID: 23990122 Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical