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. 2010 Apr;54(4):1650-1.
doi: 10.1128/AAC.01821-09. Epub 2010 Feb 1.

In vitro activity of penem-1 in combination with beta-lactams against blaKPC-possessing Klebsiella pneumoniae isolates

Andrea Endimiani, Christopher Bethel, Yuvraj Choudhary, Robert A Bonomo

In vitro activity of penem-1 in combination with beta-lactams against blaKPC-possessing Klebsiella pneumoniae isolates

Andrea Endimiani et al. Antimicrob Agents Chemother. 2010 Apr.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Distributions of MICs of piperacillin, aztreonam, cefotaxime, and cefepime and their combinations with penem-1 (Pen-1) obtained using the agar diffusion method. Results were interpreted according to CLSI criteria (3). Dashed line, susceptibility (S) cutoff.
See this image and copyright information in PMC

References

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    1. CLSI.2009. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard, 8th ed. CLSI document M7-A8. Clinical and Laboratory Standards Institute, Wayne, PA.
    1. CLSI.2010. Performance standards for antimicrobial susceptibility testing: 20th informational supplement. CLSI document M100-S20. Clinical and Laboratory Standards Institute, Wayne, PA.
    1. Endimiani, A., J. M. Depasquale, S. Forero, F. Perez, A. M. Hujer, D. Roberts-Pollack, P. D. Fiorella, N. Pickens, B. Kitchel, A. E. Casiano-Colon, F. C. Tenover, and R. A. Bonomo.2009. Emergence of blaKPC-containing Klebsiella pneumoniae in a long-term acute care hospital: a new challenge to our healthcare system. J. Antimicrob. Chemother. 64:1102-1110. - PMC - PubMed
    1. Endimiani, A., A. M. Hujer, F. Perez, C. R. Bethel, K. M. Hujer, J. Kroeger, M. Oethinger, D. L. Paterson, M. D. Adams, M. R. Jacobs, D. J. Diekema, G. S. Hall, S. G. Jenkins, L. B. Rice, F. C. Tenover, and R. A. Bonomo.2009. Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA. J. Antimicrob. Chemother. 63:427-437. - PMC - PubMed

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